专业概况
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Programme description
Our PhD/MPhil Pharmacology programme enables you to undertake a research project that will improve understanding of Pharmacology.
Our pharmacology research focuses on a range of topics. These include:
- the pharmacology of drug efflux transporters, particularly ABCB1 P-glycoprotein, ABCG2 breast cancer resistance protein and ABCC multidrug resistance-associated transporters;
- developing complex, physiologically-relevant in vitro cell systems to investigate transport, metabolism and delivery of therapeutic drugs;
- understanding the pharmacological and molecular mechanisms that regulate expression and function of drug efflux transporters, particularly in the blood-brain barrier;
- the role of blood-brain barrier drug efflux transporters in drug delivery to the central nervous system and the effects of inflammatory and degenerative conditions, eg Alzheimer's disease, on efflux transporter function;
- the biological role of lipid networks in health and disease, particularly their roles in inflammation, cellular communications and tissue responses;
- employing mass spectrometry-based lipidomic technology, in conjunction with functional, metabolic and signaling approaches to characterise lipid profiles in physiological and pathophysiological conditions;
- investigating the role of lipids in skin homeostasis and in response to inflammation, injury and wound healing;
- studying role of local hormones in diseases and conditions associated with the female reproductive tract (eg dysmenorrhoea, endometriosis and the detection and prevention of preterm labour);
- molecularly identifying and pharmacologically characterising receptors expressed in the female reproductive system;
- understanding the physiological and pharmacological characteristics of the placenta. These studies include the development of placental homing peptide-microRNA inhibitor conjugates for targeted enhancement of placental growth signaling.
Teaching and learning
PhD/MPhil programmes are based on individual research projects that last three to four years (PhD) or one year (MPhil), working with a specific Primary Supervisor and Co-Supervisor(s).
Applicants are specifically matched with a Primary Supervisor and individual project based on their research interests and background.
Career opportunities
Your postgraduate research degree will open up a range of career opportunities after you graduate.
所属院系
进入哪个院系学习? Faculty of Biology, Medicine and Health
中国学生入学要求
课程信息
学制:全日制(1 年)
学费:
开学时间:2022九月
申请截止日期:
留学地点:The University of ManchesterOxford Road,Manchester,M13 9PL, England